For Pre and Post Column Applications
Advantage Flow Splitters make it easy to create split ratios from 1:1 up to as high as 20,000:1
and are available in three distinct formats: fixed, adjustable, and multi-port fixed. Splitters are available for both analytical
range flows of 0.1-10mL/min and prep flow rates of 5.0-40mL/min.
The Fixed Flow Splitter provides a fixed split ratio with an extremely low dead volume. Delay volume on the low flow/capillary side is as low as 100 nanoliters depending upon the resistor cartridge selected. The flow split ratio is not affected by changes in solvent viscosity, density or pressure and is extremely stable and reproducible. Unlike conventional splitters that use long lengths of capillary tubing, the Fixed Flow Splitter uses compact fluid resistor elements which are cartridges designed for easy replacement. Because of the extremely low internal volume of the fluid resistors, the solvent composition in both resistors at any instant in time is the same, therefore, viscosity changes associated with gradient runs do not impact the split ratio. Flow rate and viscosity changes will change the back pressure generated by the splitter, but will not affect the actual split ratio. Our Flow Splitters are configured for either post-column or pre-column applications.
The Adjustable Flow Splitter incorporates a metering valve, enabling split ratios to be modified frequently with flow changes that are stable and reproducible. The flow path contains two fluid resistors that form a parallel flow path. The low flow stream passes through a fixed resistor while the high flow rate passes through an adjustable fluid resistor (metering valve).
Both the fixed and adjustable flow splitter can be used for isocratic or gradient applications. Running gradients with solvents of different viscosities may result in a reproducible change to the split ratio.
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Model 62 Post Column Adjustable Flow Splitters
Analytical Range: 0.1 - 5mL/min Incoming Flow
Adjustable Semi-Prep Flow Splitters
Analytical Range: 5.0 - 40mL/min Incoming Flow
Replacement Inlet Filters for Adjustable Flow Splitters
Replacing the inlet filter prevents the splitter from clogging
|66-063||Replacement Analytical Inlet Filter, 2µm x 0.063 dia., 5/pkg|
|Model 62 Pre-Column Adjustable Flow Splitters
Analytical Range: 0.1 - 1mL/min Incoming Flow
Pre-Column splitting is used for micro, capillary and nano HPLC applications. The split ratio created by the splitter valve will remain constant, however, when an HPLC column is installed there will be added resistance on the flow rate channel. This added resistance must be considered to ensure the fluid resistor selected for the flow splitter provides the correct split ratio.
When ordering a pre-column flow splitter, please provide the column flow rate and back pressure specifications. If these specifications are not provided, the pre-column flow splitter will be configured assuming a 0.5mL/min inlet flow rate and a pressure drop across the column of 1500psi.
These splitters will produce under 3500 PSI back pressure with water at 0.5mL/min
|60-101||Adjustable Pre-Column Splitter, Split Ratio Range 50:1 - 1000:1|
|60-103||Adjustable Pre-Column Splitter, Split Ratio Range 15:1 - 250:1|
|60-104||Adjustable Pre-Column Splitter, Split Ratio Range 5:1 - 100:1|
|60-106||Adjustable Pre-Column Splitter, Split Ratio Range 1:1 - 20:1|
|Model 63 and 53 Fixed Binary and
Multiport Flow Splitters
• Fixed metering for precise control
• Fluid Resistor Technology
• Split ratios from 1:1 to 2,000:1
• Low dead volume
• Rugged stainless steel design
|The Advantage Fixed Flow Splitters are shipped with resistors installed that deliver the nominal stated split ratio. The split
ratios have a tolerance range of ±10%. The exact split ratio is measured and is stated on the certificate shipped with the splitter.
The input flow rate can be adjusted to compensate for the tolerance in split ratios. For instance, a 10% increase in input flow rate will
result in a 10% increase in flow at both the capillary and waste stream channels. Flow rate and viscosity changes will change
the backpressure generated by the splitter, but will not affect the actual split ratio.
These fixed Flow Splitters can be used for LC/MS, Flow Fractionation, Column Flow Splitting and Capillary Chromatography.
Model 63 Post Column Binary Fixed Flow Splitters
Analytical Range: 0.1-5mL/min Incoming Flow
|63-111||Mounting Bracket for Fixed Splitter|
|Replacement Inlet Filters
Replacing the inlet filter prevents clogging of the splitter
|77-125||Binary Analytical Inlet Filter, 2µm x 0.063 dia., 5/pkg|
|Replacement Resistors for Post Column Binary Flow Splitters|
|63-443||Replacement Binary Resistor, Ratio 1:1|
|63-442||Replacement Binary Resistor, Ratio 3:1|
|63-441||Replacement Binary Resistor, Ratio 5:1|
|63-440||Replacement Binary Resistor, Ratio 10:1|
|63-439||Replacement Binary Resistor, Ratio 20:1|
|63-438||Replacement Binary Resistor, Ratio 50:1|
|63-437||Replacement Binary Resistor, Ratio 100:1|
|63-436||Replacement Binary Resistor, Ratio 200:1|
|Semi-Prep Post-Column Binary Flow Splitters
Analytical Range: 5.0-40mL/min Incoming Flow
Prep Range: 5.0-40mL/min Incoming Flow
|63-405||Binary Fixed Splitter, Ratio 500:1|
|63-410||Binary Fixed Splitter, Ratio 1,000:1|
|63-402||Binary Fixed Splitter, Ratio 2,000:1|
|Replacement Resistors for Semi-Prep Post-Column Binary Fixed Splitters|
|63-435||Replacement Binary Resistor, Ratio 500:1|
|63-434||Replacement Binary Resistor, Ratio 1,000:1|
|63-433||Replacement Binary Resistor, Ratio 2,000:1|
Model 53 MultiPort Fixed Flow Splitter Manifold
Analytical Range: 0.1 - 5mL/min Incoming Flow
|Multiport Splitters come mounted on a Mounting Bracket|
|53-112||3 Port Fixed Splitter, Post-Column, Custom Ratio|
|53-114||4 Port Fixed Splitter, Post-Column, Custom Ratio|