Para-dox® Aluminum Reaction Blocks
A successful approach to high-throughput reaction screening requires the best tools available. Our comprehensive line of photoredox catalysis and parallel synthesis reaction blocks is exactly what you need. Designed specifically for high-throughput screening (HTS) applications, the SBS (SLAS/ANSI) format allows for use in any industry standard automation application. Within each reaction block are silicone mats for compression sealing, as well as PFA films to keep glass vials (your samples) from sticking to the silicone mats during heating. This sealing strategy has resulted in our reaction blocks being validated to have less than 5% solvent loss, even with prolonged heating.
Para-dox® reaction blocks:
- Useful for generating compound arrays (medicinal chemistry)
- Useful for conducting screening reaction conditions
- Can be used on tumble stirrers / hot plate stirrers / robotic platforms
- Can easily be used in a glovebox
- Use with our pre-loaded vial trays in both standard and micro sizes (suggested for quick and easy loading)
We also offer a wide array of accessory items, providing options for a variety of application requirements.
Gen II reactors:
For 24 well reactors, the ideal torque value is 18 in•lbs. Start with the center bolt first, then go top left, bottom right, bottom left, top right. Go around at least twice until you get to 18 in•lb. Be sure to never tighten 1 bolt fully before engaging the others. See Gen II Reactor Block Setup.
For 48 and 96 well, the ideal torque values are 20 in•lbs and 18 in•lbs respectively. Start at the top left, then go bottom right, bottom left, top right. Go around at least twice. First time around try to go 10 in•lbs, then the 2nd time around you can go to 20 (for 48) or 18 (for the 96) in•lbs. Again, never tighten 1 bolt fully before engaging the others. See Gen II Reactor Block Setup.
Gen I reactors:
A torque of 5.3 inch-pounds (0.60 Newton-meters) is recommended. See Aluminum reaction Block Setup.
Generating a firm seal requires that the torque on each screw be as equal as possible. The user may need to retrace their star pattern several times as tightening one screw will slightly decrease the load on another.